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What are zymogens?

asked : 10 months, 7 days ago Biology

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Visitor 1548681055 posted an answer
10 months, 7 days ago

Zymogens, or proenzymes, are enzymes secreted in inactive form. Under certain conditions, a zymogen changes into the active form of the enzyme. In general, zymogen secretions happen because enzyme activity can harm secretory tissue.

For example, the pepsinogen secreted by the stomach becomes active under an acidic pH, turning into the enzyme pepsin. Other well-known zymogens are trypsinogen and chymotrypsinogen, enzymes that are secreted by the exocrine pancreas and which become trypsin and chymotrypsin respectively.
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